Annual report pursuant to Section 13 and 15(d)

Note 1 - Nature of Business and Significant Accounting Policies (Details Textual)

v3.7.0.1
Note 1 - Nature of Business and Significant Accounting Policies (Details Textual)
$ in Thousands
12 Months Ended
Dec. 28, 2016
Dec. 31, 2016
USD ($)
Dec. 31, 2015
USD ($)
Number of Reportable Segments   1 1
Goodwill, Impairment Loss   $ 15,666
Impairment of Intangible Assets, Finite-lived   $ 3,400 $ 0
Reverse Stock Split [Member]      
Stockholders' Equity Note, Stock Split, Conversion Ratio 10    
Minimum [Member]      
Finite-Lived Intangible Asset, Useful Life   2 years  
Maximum [Member]      
Finite-Lived Intangible Asset, Useful Life   9 years  
Furniture and Fixtures [Member] | Minimum [Member]      
Property, Plant and Equipment, Useful Life   7 years  
Furniture and Fixtures [Member] | Maximum [Member]      
Property, Plant and Equipment, Useful Life   10 years  
Office Equipment [Member] | Minimum [Member]      
Property, Plant and Equipment, Useful Life   2 years  
Office Equipment [Member] | Maximum [Member]      
Property, Plant and Equipment, Useful Life   5 years  
Lab Equipment [Member] | Minimum [Member]      
Property, Plant and Equipment, Useful Life   5 years  
Lab Equipment [Member] | Maximum [Member]      
Property, Plant and Equipment, Useful Life   7 years  
Leasehold Improvements [Member] | Minimum [Member]      
Property, Plant and Equipment, Useful Life   4 years  
Leasehold Improvements [Member] | Maximum [Member]      
Property, Plant and Equipment, Useful Life   5 years  
Software for Internal Use [Member] | Minimum [Member]      
Property, Plant and Equipment, Useful Life   3 years  
Software for Internal Use [Member] | Maximum [Member]      
Property, Plant and Equipment, Useful Life   7 years  
Software for External Use [Member]      
Property, Plant and Equipment, Useful Life   3 years