Annual report pursuant to Section 13 and 15(d)

Preferred Stock and Equity Offerings (Details Narrative)

v3.8.0.1
Preferred Stock and Equity Offerings (Details Narrative) - USD ($)
1 Months Ended 3 Months Ended 12 Months Ended
Oct. 12, 2017
Jul. 31, 2017
Jul. 07, 2017
Jul. 05, 2017
Jun. 21, 2017
Jun. 21, 2017
Jun. 16, 2017
Apr. 18, 2017
Mar. 22, 2017
Mar. 22, 2017
Feb. 08, 2017
Jan. 25, 2017
Jan. 06, 2017
Apr. 18, 2017
Feb. 28, 2017
Dec. 31, 2016
Sep. 30, 2017
Dec. 31, 2017
Dec. 31, 2016
Oct. 31, 2014
Preferred stock, shares authorized                               5,000,000   5,000,000 5,000,000  
Net proceeds from equity offerings   $ 960,000                               $ 29,900,000    
Number of common stock issued, shares           9,900,000                            
Proceeds from issuance of common stock                                   23,081,000 $ 1,707,000  
Warrants to purchase shares of common stock   875,000                                    
Proceeds from issuance or sale of equity                                   29,900,000    
Fair value of warrants issued                                 $ 200,000 141,000  
Option to purchase overallotment option, percentage             4.00%                          
Warrant term       3 years                                
Debt conversion, converted instrument, amount                                   11,643,000  
Loss on conversion of convertible debt                                   $ 4,300,000    
Underwriters' overallotment option to purchase common stock   875,000         1,875,000                          
Debt instrument beneficial percentage, description                                   The company offered to each purchaser whose purchase of shares of common stock in this offering would otherwise result in the purchaser, together with its affiliates and certain related parties, beneficially owning more than 4.99% of our outstanding common stock immediately following the consummation of this offering, the opportunity to purchase, if the purchaser so chooses, pre-funded warrants, in lieu of shares of common stock that would otherwise result in the purchaser’s beneficial ownership exceeding 4.99% of our outstanding common stock. Subject to limited exceptions, a holder of pre-funded warrants could not have the right to exercise any portion of its pre-funded warrants if the holder, together with its affiliates, would beneficially own in excess of 4.99% (or, at the election of the holder, 9.99%) of the number of shares of common stock outstanding immediately after giving effect to such exercise. Each pre-funded warrant was exercisable for one share of our common stock.    
Warrant exercised                                   1,700,000    
Warrant exercise price $ 1.25     $ 1.25                                
Underwriters purchase common stock, value   $ 960,000                                    
Proceeds from warrants                                   $ 193,000    
Warrant expiring date       Aug. 31, 2020                                
Warrants exercisable into common stock       150,000                                
Other (expense) income, net                                   (2,128,000) 14,000  
Gross proceeds from warrant exercise                                   2,100,000    
Underwriter Discount [Member]                                        
Underwriters purchase common stock, value   72,000                                    
Proceeds from warrants   $ 882,000                                    
RedPath Note [Member]                                        
Repayments of debt                               $ 1,330,000        
Debt instrument principal amount                               9,340,000     9,340,000 $ 10,700,000
RedPath Note [Member] | Senior Secured Non-Convertible Note [Member]                                        
Debt instrument principal amount                 $ 3,550,000 $ 3,550,000               $ 3,550,000    
Debt conversion, converted instrument, amount               $ 3,550,000                        
Debt conversion, converted instrument, shares issued               3,795,429           3,795,429            
RedPath Note [Member] | Investor [Member]                                        
Fair value of warrants issued                   500,000                    
Acquisition of debt                   $ 8,870,000                    
RedPath Note [Member] | Investor [Member] | Senior Secured Non-Convertible Note [Member]                                        
Debt instrument principal amount               $ 3,550,000           $ 3,550,000            
RedPath Note [Member] | RedPath Integrated Pathology, Inc [Member]                                        
Debt instrument principal amount                               9,340,000     9,340,000  
Senior Secured Convertible Note [Member]                                        
Debt instrument principal amount                               5,320,000     5,320,000  
Senior Secured Non-Convertible Note [Member]                                        
Debt instrument principal amount                               $ 3,550,000     $ 3,550,000  
Termination Agreement [Member] | RedPath Equityholder Representative [Member]                                        
Warrants to purchase shares of common stock                 100,000 100,000                    
Common stock purchase price per share                 $ 4.69 $ 4.69                    
Fair value of warrants issued                 $ 190,000                      
Warrant term                 5 years                      
Employee Severance [Member]                                        
Payments for restructuring                             $ 1,000,000          
Private Placement [Member]                                        
Warrant exercise price 1.80                                      
First Registered Direct Offering [Member]                                        
Number of common stock issued, shares                         630,000              
Common stock price, per share                         $ 6.81              
Proceeds from issuance of common stock                         $ 4,300,000              
Second Registered Direct Offering [Member]                                        
Number of common stock issued, shares                       855,000                
Fair value of warrants issued                       $ 1,670,000                
Second Registered Direct Offering [Member] | Employee Severance [Member]                                        
Payments for restructuring                       $ 1,000,000                
Second Registered Direct Offering [Member] | Private Placement [Member]                                        
Warrants to purchase shares of common stock                       855,000                
Common stock purchase price per share                       $ 4.69                
Proceeds from issuance or sale of equity                       $ 4,000,000                
Confidentially Marketed Public Offering (CMPO) [Member]                                        
Number of common stock issued, shares                     1,200,000                  
Common stock price, per share                     $ 3.00                  
Proceeds from issuance or sale of equity                     $ 3,900,000                  
Option to purchase overallotment option, percentage                     9.00%                  
Common Stock [Member]                                        
Number of common stock issued, shares                                   34,000  
Warrants to purchase shares of common stock             9,900,000                          
Base Warrants [Member]                                        
Net proceeds from equity offerings           $ 13,700,000                            
Number of common stock issued, shares           12,500,000                            
Warrants to purchase shares of common stock             12,500,000                          
Common stock purchase price per share             $ 1.25                          
Fair value of warrants issued           $ 5,300,000                            
Common stock effective purchase price             $ 1.10                          
Underwriters' overallotment option to purchase common stock             1,875,000                          
Underwriter Warrants[Member]                                        
Number of common stock issued, shares         575,000                              
Warrants to purchase shares of common stock             2,600,000                          
Common stock purchase price per share             $ 0.01                          
Warrant exercise price                                   $ 1.32    
Base Warrant And Prefunded Warrants [Member]                                        
Common stock effective purchase price             $ 1.09                          
Oveallotment Warrants [Member]                                        
Warrants to purchase shares of common stock         1,875,000 1,875,000                            
Common stock purchase price per share         $ 0.01 $ 0.01                            
Pre-Funded Warrants [Member]                                        
Net proceeds from equity offerings           $ 12,300,000                            
Number of common stock issued, shares           2,600,000                            
Warrants to purchase shares of common stock     2,600,000       2,600,000                          
Common stock purchase price per share             $ 1.09                          
Fair value of warrants issued     $ 2,300,000                                  
Underwriting discount rate             7.50%                          
Offering and over-allotment and reasonable out-of-pocket expenses             $ 100,000                          
Warrant exercised     2,600,000                                  
Warrant exercise price     $ 0.01       $ 1.09                     $ 0.01    
Proceeds from warrants     $ 26,000,000                                  
Overallotment Warrants [Member]                                        
Number of common stock issued, shares         1,875,000                              
Fair value of warrants issued         $ 800,000                              
4 Million Base Warrants [Member]                                        
Common stock purchase price per share $ 1.25                                      
Proceeds from warrants $ 5,000,000                                      
Other (expense) income, net $ 2,000,000                                      
4 Million Base Warrants [Member] | Private Placement [Member]                                        
Warrants to purchase shares of common stock 3,200,000                                      
Warrant exercise price $ 1.80